By Debjani Baidyaray
Mumbai, February 04: A new research on type 2 diabetes by the researchers from Trinity College Dublin can benefit the young type 2 diabetics. This research has been published online in
Diabetes Care, an leading international journal.
Diabetes, a metabolic disorder characterized by high blood sugar level and insulin resistance, is mainly of two types, type 1 and 2. Type 2 is hereditary to a large extent and can be inherited from immediate relatives already having the condition. This new study, led by Professor John Nolam of Trinity College Dublin and St James's Hospital, Dublin demonstrates new mechanisms in muscle cells that may help explain insulin resistance. This resistance also indicates reduced response to aerobic exercise in young obese diabetics. The findings of the study will help in development of treatment procedures for young adults suffering from type 2 diabetes.
Diabetes, known to a condition only meant for adults in their middle and old ages are now affecting young adults due to the changing lifestyle. Lack of physical activity, improper diet with more caloric food, and increasing weight gain contribute to develop the condition in their early twenties. Type 2 diabetes accounts for about 85 to 90 percent of diabetes cases in Europe and is estimated to rise further in near future.
Cases of early obesity and a family background of diabetes is affecting younger people more. This new research provides new and important insights on how the condition develops and progresses and has how young obese diabetics have abnormal key mitochondrial genes and proteins compared to obese young people without diabetes. Aerobic and other physical exercise helps control type 2 diabetes to a great extent but the abnormalities in the mitochondria, the energy center in cells attribute to reduced response to such activities.
According to the World Health Organization (WHO), by 2025 more than 75 percent of people with diabetes will be from India. Diabetes is found to be affecting more Asians and with this research, specific treatment for these young diabetics can be designed depending on a more extact understanding of the cellular mechanisms of this condition.
The research was carried out by the Metabolic Research Unit at Trinity College Dublin based at St James's Hospital.
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TAGS: Diabetes, Type 2 diabetes, young diabetics, obesity
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